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Calorimetric and Spectrophotometric Studies of Poly-Lysine Nanoparticles in the Presence of Farnesal

Author: Levan Shvelidze
Keywords: Nanoparticles, Poly-Lysine, Farnesal
Annotation:

Nanoparticles have garnered significant attention in recent years due to their unique physical, chemical, and biological properties that arise from their small size and large surface area-to-volume ratio. These properties make nanoparticles valuable in a wide range of applications, from medicine to electronics. This Master's thesis aims to provide a comprehensive analysis of the synthesis methods, properties, and applications of nanoparticles, with a specific focus on poly-lysine and farnesal nanoparticles. Poly-lysine is a biodegradable polymer known for its high efficiency in biological systems, while farnesal is a biologically active compound that exhibits unique properties in various biological contexts. The primary objective of this research is to analyze the physical and chemical properties of poly-lysine and farnesal nanoparticles using calorimetric and spectrophotometric methods. Calorimetry allows for the investigation of the thermal properties of nanoparticles, providing insights into their phase transitions and stability under different conditions. Spectrophotometry, on the other hand, is used to study the optical properties of nanoparticles, including their absorption and emission spectra. Together, these techniques offer a detailed understanding of the interactions between poly-lysine and farnesal at the nanoscale. The research employs a DASM-4A calorimeter and a high-sensitivity spectrophotometer to conduct the experiments. These instruments enable precise measurements of the thermal and optical characteristics of the nanoparticles, facilitating a thorough analysis of their phase transitions and thermal properties. The results of this study indicate that the combination of poly-lysine and farnesal leads to the formation of nanoparticles with distinct thermal and optical properties. These properties are influenced by factors such as the concentration of farnesal, the temperature, and the pH of the solution. The findings suggest potential applications of these nanoparticles in the development of new diagnostic and therapeutic methods, leveraging their unique properties for targeted drug delivery and advanced medical imaging techniques. The detailed investigation of the calorimetric and spectrophotometric properties of poly-lysine and farnesal nanoparticles contributes to the broader understanding of biopolymer-based nanoparticles and their interactions with biologically active compounds. This research represents a significant step forward in the study of nanoparticle-based systems, highlighting their potential for innovative applications in biomedicine, environmental science, and beyond. In conclusion, the study of poly-lysine and farnesal nanoparticles using calorimetric and spectrophotometric methods provides valuable insights into their unique properties and potential applications. The findings underscore the importance of further research into the synthesis and characterization of biopolymer-based nanoparticles, paving the way for the development of new technologies and approaches in various scientific fields


Lecture files:

ალორიმეტრული და სპექტროფოტომეტრული კვლევები Poly-Lysine ნანონაწილაკების პრეპარატ ფარნესალის თანაობისას [ka]

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