Addition reaction of Acetylated Allylgalactopyranoside with Triphenylchlorosilane

Author: Anano Todua
Keywords: Carbohydrate, Allylated O- Glycoside, Triphenylchlorosilane, Triphenylsilane, Dicumil Peroxide
Annotation:

Annotation Anano Todua Addition reaction of Acetylated Allylgalactopyranoside with Triphenylchlorosilane Department of Chemistry, Iv.Javakhishvili Tbilisi State University, Ilia Chavchavadze Ave. 3 For the development of a living organism, silicon compounds perform important functions. In addition, the introduction of a silicon atom into known medicinal preparations may significantly change the nature of the drug's action, and in some cases add new properties to them. The Addition reaction of 1-O-Allyl-2,3,4,6-tetra-O-acetyl-β-D-galaqtopiranoside (5) with triphenylchloro¬si¬la¬ne (6) in the presence of a dicumyl peroxide catalyst, gave 1-O-(2-chloro-3-triphenyl silyl)-propyl-2,3,4,6-tetra-O-acetyl-β-D-galaqtopyranoside (7). The reac-t¬ion basically proceeds according to Markovnikov's rule. The reaction proceeds according to the following scheme: The structure of the synthesized compounds was determined by physico-chemical research methods.